Web Definition: Rheumatoid Arthritis
Rheumatoid arthritis is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. It is a disabling & painful inflammatory condition, which can lead to substantial loss of mobility due to pain & joint destruction. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs & muscles. Arthritis & soft-tissue swelling of >3 of 14 joints/joint groups. Rheumatoid factor at a level above the 95th percentile. Radiological changes suggestive of joint erosion. Four criteria have to be met, although many patients are treated despite not meeting the criteria. The symptoms that distinguish rheumatoid arthritis are inflammation & soft-tissue swelling of many joints at the same time. The hands are generally affected in a symmetric fashion. The pain generally improves with use of the affected joints & there is usually stiffness of all joints in the morning that lasts over 1 hour.
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