Web Definition: Celebrex
Celecoxib is a medicinal drug best known as a Pfizer product with the brand name Celebrex. Celecoxib is used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation & menstrual symptoms & to reduce numbers of colon & rectum growths polyps in patients with familial adenomatous polyposis. It is classified as a nonsteroidal anti-inflammatory drug, or NSAID & should not be taken by anyone allergic to NSAIDs. Celecoxib is a highly selectived COX-2 inhibitor since it primarliy acts on one specific form of the cyclooxygenase enzyme, whereas other NSAIDs inhibit both COX-1 & COX-2. Celecoxib is 10-20 times more selective for COX-2 than for COX-1. This specificity allows Celecoxib & other COX-2 inhibitors to reduce inflammation while minimizing undesired side effects that can occur with non-selective NSAIDs. Celecobix is a & consequently may cause rashes. It does not alter platelet aggregation & causes fewer endocopic ulcers that other NSAIDs.
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